CORNELIUS F. IVORY Dept. Chemical Engineering B43 EE/ME Building Washington State University P.O. Box 642710 Pullman, WA 99l64-27l0 Office: (509) 335-7716 FAX: (509) 335-4806 e-mail: cfivory at wsu.edu Microchip ITP Link 1987 Science Cover EDUCATION. 1980 Princeton University, Ph.D. Chemical Engng 1976 Princeton University, Master of Arts in Chemical Engng 1974 University of Notre Dame, B.S. Chemical Engng PROFESSIONAL EXPERIENCE. Councilor, American Electrophoresis Society, 10/05 - present Senior Fellow, Biomedical Engineering Center, U. New Mexico, 05/05 - present Associate Director, NIH Predoctoral Program in Biotechnology 9/01 - present Sabbatical Leave at University of Delaware, 9-12/03 Washington State University 1989-present University of Notre Dame, 1980-1987 FMC Corporation, COGAS Division, design engineer, 1980 USRA Visiting Scientist at NASA's Marshall Space Flight Center, 1979-1980 Cities Service Research Center, Cranbury, New Jersey, Research Engr., 1975-1976 CURRENT COURSES. ChE 334: Chemical Engineering Separations ChE 433: Undergraduate Unit Operations Lab ChE 435: Modern Separation Processes ChE 475: Introduction to Biochemical Engineering ChE 541: Chemical Engineering Analysis. ChE 574: Protein Biotechnology ChE 561: Downstream Processing ChE 596: Research Methods I. ChE 597: Research Methods II ChE 598: Research Seminar RESEARCH AREAS. Biological Separations: Electrophoresis and Electrochromatography Fractionation of Organelles from S. cerevisiae Protein Transport in Ion Exchange Resins: Ann-Marie Hardin Electrophoretic Enantiomer Fractionation: Brian Thome Dynamic Field Gradient Focusing: Jeff Burke Fast Preparative Isoelectric Focusing: Danny Bottenus Preparative Field-Gradient Focusing: Noah Tracy Micropreparative Purification of Protein Isoforms: Huanchun Cui Mass Balancing of Low-Abundance Proteins: Schurie Moreau Isotachophoresis (ITP) Membrane Separations: Electro-Ultrafiltration Process Stability: Hydrodynamic and electrical instabilities Spatial patterning in conductive films and membranes The NIH Biotech Program is open to ChEs for graduate training. PROFESSIONAL RECOGNITION. Program Co-Chair, American Electrophoresis Society, CEPharm Meeting, Jersey City, 10/06 Outstanding Researcher, School of Chemical Engineering and Bioengineering Program Co-Chair, American Electrophoresis Society, 11/03 National Meeting in San Francisco Associate Director, NIH Predoctoral Program in Biotechnology 9/01 - present Editorial Board, Separation Science and Technology, 1997-present Outstanding Teacher Award, WSU Department of Chemical Engineering, 1990 Editorial Advisory Board, Industrial and Engineering Chemistry Research, 1990 Special Issue Editor, Separation Science and Technology, 1988 National Program Committee Chair, Industrial & Engng. Chem. Div., ACS, 1987-1990. BOOK CHAPTERS (Since 1999). Alternative Focusing Techniques, Ivory, C. F., in the Handbook of Isoelectric Focusing and Proteomics, S. Ahuja and D. Garfin, eds., CRC Press 2005 Chapter 9: "Electrophoresis of Proteins: Batch and Continuous Methods, in The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis and Bioseparations, M. Flickinger and S. Drew, eds., John Wiley and Sons, Inc. 1999 RECENT PUBLICATIONS. (Full Curriculum Vitae PDF) Leatzow, D. and C. F. Ivory, “Preparative-scale Isoelectric Focusing of Protein Isoforms in a Vortex-Stabilized Electrophoresis Device,” Final draft Horiuchi K., P. Dutta and C. F. Ivory, “Electroosmosis with Step Changes in Zeta Potential in Microchannel Electrophoresis,” Final draft Cui, H., Al Mamun, N. H., Z. Huang, P. Dutta and C. F. Ivory, “Dynamic Electric Valving for Electrokinetic Separation in a Networked Microfluidic Chip,” Final draft Thome, B. and C. F. Ivory, “Increasing the Scale of True Moving Bed electrophoretic separations using filtration to reduce solvent volumetric flows between sections II and III,” Submitted Shim J-S., P. Dutta and C. F. Ivory, “Modeling and Simulation of Isoelectric Focusing in Two-Dimensional Geometries,” Submitted Harrison, S. and C. F. Ivory, “An Analytical Expression which Predicts the Location of Stationary, Steady-State Zone Positions in Isotachophoresis,” Submitted Cui, H., Al Mamun, N. H., P. Dutta and C. F. Ivory, “Isotachophoresis of Proteins in a Microfluidic chip with T-Junctions: Experiment and 2D Simulation,” Submitted Hardin, A. M. and C. F. Ivory, “Buffer salt effect on pH in the interior of an anion exchange resin,” J. Colloid Interface Sci., Accepted Thome, B. and C. F. Ivory, “Continuous Voltage Gradients and Their Application to True Moving Bed Electrophoresis,” J. Chromatogr. Accepted Bottenus D., Leatzow, D., and C. F. Ivory, “Effects of Increased Voltage on Resolution in Isoelectric Focusing of Myoglobin Variants,” Electrophoresis Accepted Bottenus, D. and C. F. Ivory, “On-Line Optical Fiber Detection in a Preparative Vortex-Stabilized Free-Flow Electrofocusing Apparatus,” Biotechnology Progress 22(3): 842-846 (2006). Cui, H., K. Horiuchi, P. Dutta and C. F. Ivory, “Multistage isoelectric focusing in a Poly(dimethylsiloxane) microfluidic chip,” Analytical Chemistry 77(24):7878-86 (2005). Petsev, D. N., G. P. Lopez, C. F. Ivory, S. S. Sibbett, “Microchip Protein Separation by Electric Field Gradient Focusing," Lab-on-a-Chip, 5(6) 587-597 (2005). Cui, H., K. Horiuchi, P. Dutta and C. F. Ivory, “Isoelectric focusing in a Poly(dimethylsiloxane) microfluidic chip," Analytical Chemistry, (2005). Ivory, C. F., “Preparative Free-Flow Electrofocusing in a Vortex-Stabilized Annulus,” Electrophoresis, 25 360-374 (2004). Ross, D., C. F. Ivory, L. E. Locascio, and K. E. Van Cott, “Peak Compression and Resolution for Electrophoretic Separations in Diverging Microchannels,” Electrophoresis, 25(21-22) 3694-3704 (2004). Tracy, N. and C. F. Ivory, “Modeling Two-Component Isoelectric Focusing Buffers in a Vortex-Stabilized Electrophoresis Apparatus,” Biotechnol. Progress 20(1) 193-199 (2004) Preparative Focusing of Proteins Using Binary Buffers in a Vortex-Stabilized, Free-Flow Apparatus,” Electrophoresis 25(12) 1748-1757 (2004). Ista, L. K., G. P. Lopez, C. F. Ivory, M. J. Ortiz, T. A. Schifani, C. D. Schwappach, and S. S. Sibbett, Microchip Countercurrent Electroseparation, Lab-on-a-Chip, 3 266-272 (2003) Ross, D., C. F. Ivory, L. E. Locascio, and K. E. Van Cott, Peak Compression and Resolution for Electrophoretic Separations in Diverging Microchannels, Anal. Chem., (2003) Submitted Thome, B. and C. F. Ivory, Development of a Segmented Model for a Continuous Electrophoretic Moving Bed Enantiomer Separation, Biotechnol. Progr., 19(6) 1703-12 (2003) Thome, B. and C. F. Ivory, "Continuous Fractionation Of Enantiomer Pairs In Free Solution Using An Electrophoretic Analog Of Simulated Moving Bed Chromatography, " J. Chromatography A 953 263-277 (2002). Ivory, C. F., "Temperature Profiles in the Thermal Entrance Region of Electrically-Heated, Laminar Flow in a Slit, Chemical Engineering Science 55 601-613 (2000). C. F. Ivory, A Brief Review of Alternative Electrofocusing Techniques, Separation Science and Technology 35(11) 1777-1793 (2000).