The Gene and Linda Voiland School of

Chemical Engineering and Bioengineering

Faculty

Bernard J. Van Wie, Ph.D.

Professor

The Gene and Linda Voiland
School of Chemical Engineering and Bioengineering
Washington State University
118 Dana Hall Spokane St.
P.O. Box 642710
Pullman, WA 99164-2710



Office: EME B57 (Tel: 509 335-4103)
Lab: ETRL 321 (Tel: 509 335-8099)
bvanwie@wsu.edu
Dr. Van Wie's Website

Graduate Students

Baba Abdul
Chris Detzel
Sarah Haarsma
Daniel Rieck

Syllabi

ChE 110 — Introduction to Chemical Engineering (Document)

ChE 301 — Introduction to Chemical Engineering Thermodynamics

ChE 332 — Fluid Mechanics and Heat Transfer (Document)

ChE 527 — Macroscopic Thermodynamics (Document)

Research Interests

Biosensing

Bioprocessing

Novel Teaching Pedagogies

Biographical Information

Dr. Van Wie earned his Ph.D. in chemical engineering from the University of Oklahoma, Norman where he focused on blood-cell separations. He did postdoctoral work in the area of natural gas and Syngas properties and has completed two sabbaticals, one at Michigan State University and one at the Naval Research Laboratory. Both sabbaticals were focused on developing novel biosensors for medicine, biotechnology, and the environment. His current research focuses on bioprocessing and biomedical engineering with applications in biosensors and miniaturized diagnostic capabilities including designs at the micro and nanoscale, cell culture, and biomass processing. He is highly interested in effective teaching, and he along with graduates and the WSU Center for Teaching, Learning, and Technology, are working on new learning pedagogy which combines some of the best learning strategies together in a single course.

Selected Publications

  1. Harvey F. Doty, Bernard J. Van Wie, Gregory Hooks, Janet E. Ebaugh, Anna L. Tester, Sarah J. Haarsma, Hajime Fuchida, Daniel C. Rieck, Rodney S. Skeen, Gary J. Cheng, Bingwen Liu, Thomas Jacroux, David A. Kidwell, Irenee R. Beattie. Design of Hands-on Learning Modules to Enhance Educational Motivation among Native High Schoolers - Cutting Edge Nanoscience Placed in an Environmental Water Quality Context. iNEER, Innovations, In Press.
  2. Metallo, C.M., Mohr, J.C., Detzel, C.J., Van Wie, Bernard J. & Palecek, S.P., "Engineering the Stem Cell Microenvironment", Biotechnology Progress, 23, 18-23, 2007.
  3. Plesha, MA, Van Wie, BJ, Mullin, JK & Kidwell, DA, "Measuring Quaternary Ammonium Cleaning Agents with Ion Selective Electrodes", Analytica Chimica Acta, 570, 186-194, 2006.
  4. Golter, P.B., Van Wie, B.J., Scuderi, P.V., Henderson, T.W., Dueben, R.M., Brown, G.R., Thomson, W.J., "Combining Modern Learning Pedagogies in Fluid Mechanics and Heat Transfer" Annals of Research in Engineering Education, 2006 Summer Issue, Vol. 2, No. 2, http://www.areeonline.org/ 2006.
  5. Golter, P, Van Wie, B, Held, G, Windsor, J, "Practical Considerations for Miniaturized Hands-on Learning Stations", Referred Conference Proceedings of the American Society for Engineering Education, Chicago, IL, June 19 - 22, 2006.
  6. Golter, P.B., Van Wie, B.J., Scuderi, P.V., Henderson, T.W., Dueben, R.M., Brown, G.R., Thomson, W.J., "Combining Modern Learning Pedagogies in Fluid Mechanics and Heat Transfer" Chemical Engineering Education, 39, 280-287, 2005.
  7. Plesha, MA, Van Wie, BJ, Kidwell, DA, "Measuring Quaternary Ammonium Cleaning Agents with Ion Selective Electrodes" Revised Manuscript Submitted to Analytica Chimica Acta.
  8. Wu, X, Van Wie, BJ and Kidwell, DA, "An Enzyme Electrode for Amperometric Measurement of d-Amino Acid", Biosensors & Bioelectronics, 20, 878-885, 2004.
  9. Wu, X, Detzel, CJ, Van Wie, BJ, Haarsma, SJ, and Kidwell, DA, "Model Based Optimization of Carbon Paste Enzyme Electrode", Biotechnology & Bioengineering, 88, 204-213, 2004.
  10. Leatzow, D.M., Van Wie, B.J., Weyrauch, B.N., and Tiffany, T.O., "Design Optimization and Characterization of a Small-Scale Centrifugal Cell Separator," Analytica Chimica Acta, 435, 299-307, 2001.
  11. Liu, G., Van Wie, B.J., Leatzow, D.M., Weyrauch, B.N., and Tiffany, T.O., "Experimental Design and Modeling of Carryover to Optimize Air-Segmented Continuous Flow Analysis, Analytica Chimica Acta, 408, 21-31, 2000.
  12. Erickson, B.H., Van Wie, B.J., Leatzow, D.M., Liu, G., Thayer, P.C. and Tiffany, T.O., "Charge Coupled Device Optics System of Simultaneous Measurement of Multiple Reactions in a Microplate", Clinical Chemistry, 44, 2046-2049, 1998.
  13. Yu, Y.-Y., Van Wie, B.J., Koch, A.R., Moffett, D.F., and Davis, W.C., "Real Time Analysis of Immunogen Complex Reactions Kinetics Using Surface Plasmon Resonance", Analytical Biochemistry, 263, 158-168, 1998.
  14. Yu, Y.-Y., Van Wie, B.J., Koch, A.R., Moffett, D.F., and Davis, W.C., "Preparation and Characterization of Bifunctional Biopolymers for Receptor-Based Liposomal Immunosensing", Biotechnology Progress, 14, 310-317, 1998.
  15. Parab, S., Van Wie, B.J., Byrnes, I., Robles, E.J., Weyrauch, B.N. and Tiffany, T.O., "Modeling & Optimization Studies for a Sequential Flow Based Bio-Analytical Module", Analytica Chimica Acta, 359, 157-171, 1998.
  16. Yu, Y.-Y., Van Wie, B.J., Koch, A.R., Moffett, D.F., Davis, W.C., "Kinetic Modeling and Analysis of a Vesicle System for Immunosensor Development", Biosensors & Bioelectronics, 12, 135-144, 1997.
  17. Reiken, S.R., Van Wie, B.J., Sutisna, H., Moffett, D.F., Koch, A.R., Silber, M., & Davis, W.C., Bispecific Antibody Modification of Nicotinic Acetylcholine Receptors for Biosensing, Biosensors & Bioelectronics, 11, 91-102, 1996.
  18. Eray, M., Dogan, N.S., Reiken, S.R., Sutisna, H., Van Wie, B.J., Koch, A.R., Moffett, D.F., Silber, M., and Davis, W.C., A Highly Stable and Selective Biosensor Using Modified Nicotinic Acetylcholine Receptor (nAChR), BioSystems, 35, 183-188, 1995.
  19. Van Wie, B.J., Poshusta, J.C., Greenlee, R.D. and Brereton, R.A., "Fun Ways to Learn Fluid Mechanics and Heat Transfer", Chemical Engineering Education, 28, 188-192, 1994.
  20. Reiken S.R., Van Wie, B.J., Sutisna, H., Kurdikar, D.L. and Davis, W.C., "Efficient Optimization of ELISAs", J. Immunolog. Meth., 177, 199-205, 1994.
  21. Eray, M., Dogan, N.S., Liu, L., Koch, A.R., Moffett, D.F., Silber, M. and Van Wie, B.J., "Highly Stable Bilayer Lipid Membranes (BLMs) Formed on Microfabricated Polyimide Apertures and Their Electrical Characterization", Biosensors and Bioelectronics, 9, 343-351, 1994.
  22. Skeen, R.S., Kurdikar, D.L. and Van Wie, B.J., "Modeling the Kinetics of Neuron-Based Chemical Sensing: Interactions Between Observable States", Biosensors and Bioelectronics, 9, 265-274, 1994.
  23. Kurdikar, D.L., Skeen, R.S. and Van Wie, B.J., "Temperature Effects on Neuron-Based Chemical Sensing in Well-Mixed Flow Environments", Analytica Chimica Acta, 262, 1-12, 1992.
  24. Skeen, R.S., Van Wie, B.J., Fung, S.J. and Barnes, C.D., "Effects of Temperature and Analyte Application Technique on Neuron-Based Chemical Sensing", Biosensors and Bioelectronics, 7, 91, 1992.
  25. Skeen, R.S., Van Wie, B.J., Fung, S.J. and Barnes, C.D., "Application of Compiled BASIC in Developing Software for Electrophysiology", J. Neuroscience Methods, 41, 113-121, 1992.
  26. Kurdikar, D.L., Skeen, R.S., Van Wie, B.J., Barnes, C.D. and Fung, S.J., "Whole Cell Biosensors: A Brief Overview and Presentation of A Novel Neuron-based Approach", In: Frontiers in Bioprocessing II, eds. Todd, P., Sikdar, S.K., and Bier, M., pp. 126-137, 1992.
  27. Wooten, S.L., Petersen, J.N. and Van Wie, B.J., "Complete Computer Control of Apheresis Procedures Performed in a COBE 2997 Cell Separator", Biomechanical Engineering, 113, 11-20, 1991.
  28. Van Wie, B.J., Brouns, T.M., Elliott, M.L. and Davis, W.C., "A Novel Continuous Centrifugal Bioreactor for High Density Cultivation of Mammalian and Microbial Cells", Biotechnology and Bioengineering, 38, 1190-1202, 1991.
  29. Skeen, R.S., Kisaalita, W.S., Van Wie, B.J., Fung, S.J. and Barnes, C.D., "Evaluation of a Neuron-Based Sensing with Neurotransmitter Serotonin," Biosensors and Bioelectronics, 5, 491-510, 1990.
  30. Skeen, R.S., Kisaalita, W.S., Van Wie, B.J., Fung, S.J., and Barnes, C. D., "Serotonin Sensing Properties of Identified Invertebrate Neurons," Biosensor Technology Fundamentals and Applications, eds: Buck, R.P., Hatfield, W.E., Umana, M. and Bowden, E.F., Marcel Dekker, Inc., New York and Basel, pp 63-69, 1990.
  31. Kisaalita, W.S., Van Wie, BJ., Skeen, R.S., Davis, W.C., Barnes, C.D., Fung, S.J., Chun, K. and Dogan, N. S., "Initiating Crossdisciplinary Research: The Neuron Based Chemical Sensor Project," Chemical Engineering Education, 23, 242-249, 1989.
  32. Van Wie, B.J., Langenberg, M.A. Chang, W.C. W., Kumar, K.H. and Starling, K.E., "Evaluation of Data Availability and Quality for Interaction Second Virial Coefficients of Use to the Gas Industry", U.S. Department of Commerce, National Bureau of Standards, Technical Note, U.S. Government Printing Office, Washington D.C., 1988.
  33. Oxford, R.J., Petersen, J.N., Van Wie, B.J., Wooten, S.L. and Schneider, G.W., "Interface Dynamics in a COBE 2997 Centrifugal Cell Separator", Transfusion, 28, 588 592, 1988.
  34. Van Wie, B.J. and Hustvedt, E.L., "Particle Interaction Effects on Blood Cell Sedimentation and Separations", Biorheology, 25, 651 662, 1988.
  35. Drumheller, P.D., Van Wie, B.J., Petersen, J.N., Oxford, R.J. and Schneider, G.W., "The Effects of RPM and Recycle on Separation Efficiency in a Clinical Blood Cell Centrifuge", Journal of Biomechanical Engineering, 109, 324 329, 1987.
  36. Van Wie, B.J., Elliott, M.L. and Lee, J.M., "Development and Characterization of a Continuous Centrifugal Bio Reactor", Biotechnology and Bioengineering Symposium, 17, 335 344, 1986.
  37. Van Wie, B.J. and Sofer, S.S., "Experimental Considerations for the Centrifugal Separation of Blood Cell Components", The International Journal of Artificial Organs, 9, 49 58, 1986.
  38. Van Wie, B.J. and Sofer, S.S., "The Effect of Recycle on the Continuous Processing of Blood Cells", The International Journal of Artificial Organs (IJAO), 8, 43 48, 1985.
  39. Van Wie, B.J. and Sofer, S.S., "Stagewise Separations to Improve Continuous Centrifugal Blood Cell Separators", IJAO, 8, 49 54, 1985.
  40. Van Wie, B.J. and Sofer, S.S., "Sedimentation Theory and Practical Considerations for the Design of Centrifugal Blood Cell Processes", IJAO, 8, 215 222, 1985.
  41. Sofer, S.S., Wills, R.A. and Van Wie, B.J., "A Model Enzymic Extracorporeal Detoxification System", Artif. Organs, 3, 127 131, 1979.

The Gene & Linda Voiland School of Chemical Engineering and Bioengineering, PO Box 642710, Washington State University, Pullman WA 99164-2710, 509-335-4332, Email ChEBE: chebe AT wsu DOT edu